Browsing by Author "Mlangwa, Mhina E."

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    Determining cutaneous markers of dyslipidemia among hiv seropositive patients on antiretroviral therapy attending care and treatment clinics in Dar es Salaam
    (Kairuki University, 2024) Mlangwa, Mhina E.
    Background: The prevalence of ischaemic heart disease (IHD) in Sub-Saharan Africa has been on the rise among people living with HIV. HIV infection and antiretroviral drugs (ARTs) are both associated with dyslipidemia. Objective: This study aimed to determine the prevalence of cutaneous markers of dyslipidemia and associated factors among HIV seropositive on ARTs attending CTCs in Dares Salaam. Method: A descriptive cross-sectional study among HIV seropositive individuals aged 18 years and above were enrolled at Kairuki Hospital and Mwananyamala Regional Referral Hospital, from February to July 2024, and a 100% response rate was obtained. The diagnosis of cutaneous markers of dyslipidemia was based on physical examination (Visual inspection by naked eye keenly looking for cutaneous markers). A fasting blood sample was obtained for serum markers of dyslipidemia Results: The study recruited 305 people, 21 persons were excluded due to missing data, and a total of 284 were analysed with a response rate of 100%. The mean age of participants was 46.7±10.9, and 182(64.1%). The mean BMI was 26.2±5.5, with 80(28.2%) were overweight. Fifty per cent of participants were on ART for 10 years or more. A total of 17(5.9%) participants were found to have cutaneous markers of dyslipidemia. No association was found between alcohol consumption, cigarette smoking, and other predictors of dyslipidemia. Conclusion: This study found the prevalence of cutaneous markers of dyslipidemia; henceforth heralding the need of incorporating lipid screening as a component of care among HIV seropositive individuals on ARTs, for reducing mortality and morbidity.