Directorate of Postgraduate Studies

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Browsing Directorate of Postgraduate Studies by Subject "Adverse child outcomes"

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    Magnitude of adverse maternal and newborn outcomes among women with pregnancy induced pre-hypertension at three regional referral hospitals, Dar es Salaam from January to April 2024
    (Kairuki Univerity, 2024) Abeid, Mwalim. A.
    Introduction : Prehypertension is a prevalent condition in maternity wards worldwide. The debate is still ongoing on the contribution of prehypertension to the occurrence of adverse birth outcomes in both mothers and neonates, specifically in low-income countries where scarce studies have been conducted in this field. This study aimed to determine the early neonatal outcome, mother outcome, and their respective factors associated with women with and without prehypertension attending antenatal clinics at the Amana, Temeke, and Mwananyamala Regional Referral Hospitals. Adverse birth outcomes and their associated factors were examined. Methods : This study was a case control study conducted among pregnant mothers with and without late prehypertension as well as their newborns from the antenatal period to one week postpartum periods. Social demographic and clinical data were collected using a pre-designed questionnaire. Data was analyzed using Statistical Package for Social Sciences. Descriptive statistics were used to summarize the data, while Chi square test was used to assess maternal and neonatal outcome among the study groups. Binary logistic regression analysis was used to assess factors associated with adverse maternal and neonatal outcome among prehypertensive pregnant women. A p value of less or equal to 0.05 was considered statistically significant. Results : A total of 330 participants were enrolled in the study. The magnitude of neonatal birth outcome and maternal outcome in pregnant mothers with late pregnancy prehypertension were of 120 (65%) and 76 (96.2%) respectively. Low Apgar score, low birth weight, still birth, and fresh still death were the most frequent adverse neonatal birth outcomes observed, with a respective rate of 44 (13%), 41 (12.4%), 30 (9%), and 4(1.2%). On the other hand, gestational hypertension followed by preeclampsia were the most common adverse maternal outcome observed in 54 (71%) and 22 (28.1%) of study participants respectively. Neonates from mothers with an age range of 20 to 24 years( OR=5.7;95%CI=2.4-6.7;P=0.04),prolonged labor(AOR=1.6;95%CI=1.4-6.2;P=0.001) and Caesarian sections(AOR=1.3; 95%CI=1.14-1.6,p=0.04) were the most affected. On the other hand, mothers with business activities (AOR=1.2; 95%CI=1.1-1.9) those with 12 children(AOR=1.4;95%CI=1.15;1.7),and those who had malpresentation (AOR=1.4;95% CI=1.15-1.5) in labor were the most affected. Conclusion: The magnitude of adverse neonatal and maternal outcomes in pregnant mothers was more frequent in participants with late pregnancy hypertension than in those with normal blood pressure. The most affected newborns were those born from caesarian sections and those whose mothers had prolonged labor.