Evaluation of ethnomedical claims and brine shrimp toxicity of some plants used in Tanzania as traditional medicines

dc.contributor.authorMoshi, Mainen J.
dc.date.accessioned2023-08-11T09:03:03Z
dc.date.available2023-08-11T09:03:03Z
dc.date.issued2006-03
dc.description.abstractUsing information from the literature it has been demonstrated that twenty one (21) plants out of 60 (35%) which are used in traditional medicine, in Tabora region (Western Tanzania), are used elsewhere for the treatment of similar conditions or their claims have proven biological results. Ethanol extracts of some of the plants exhibited low, some intermediate, and some high toxicity against brine shrimps. The brine shrimp assay results for Psorospermum febrifugum Spach (Guttiferae) [LC50 12.7µg/ml], agreed with previous reports of established anticancer activity, while for Phyllanthus engleri Pax. (Euphorbiaceae) [LC50 0.47µg/ml] they supported literature reports that it is toxic to rabbits and fish. Despite the therapeutic claims, literature reports, and brine shrimp assay results, more rigorous studies are needed to confirm the therapeutic utility of the plants.en_US
dc.identifier.citationMoshi, M.J., Mbwambo, Z.A., Nondo, R.S., Masimbaa, P.J., Kamuhabwa, A., Kapingu, M.C., Thomas, P. and Richard, M., 2006. Evaluation of ethnomedical claims and brine shrimp toxicity of some plants used in Tanzania as traditional medicines. African Journal of Traditional, Complementary and Alternative Medicines, 3(3), pp.48-58.en_US
dc.identifier.urihttps://www.journals.athmsi.org/index.php/ajtcam/article/view/117
dc.identifier.urihttp://hdl.handle.net/123456789/1113
dc.language.isoenen_US
dc.publisherAfrican Journal of Traditional, Complementary and Alternative Medicinesen_US
dc.subjectEthnomedical claimsen_US
dc.subjectDrug discovery approachesen_US
dc.subjectToxicityen_US
dc.titleEvaluation of ethnomedical claims and brine shrimp toxicity of some plants used in Tanzania as traditional medicinesen_US
dc.typeArticleen_US

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