Association of lipid profile with uterine fibroid among women attending gynecological clinic in selected hospitals Dar es Salaam Tanzania from April to June 2024
No Thumbnail Available
Date
2025
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kairuki University
Abstract
Background: Uterine fibroids are frequent findings in gynecology wards and constitute a major concern for women's well-being worldwide due to the related increased morbidity and mortality from hysterectomy, as well as an increased risk of metrorrhagia and low birth weight.
Aim of the study: This study aimed to determine the association between serum lipid profile and the presence of uterine fibroid, among women attending gynecology clinics at Kairuki, Amana, and Mwananyamala regional referral hospitals.
Materials and methods: An unmatched case-control study design was employed in this study. It involved determining the level of serum lipid and assessing the different factors associated with uterine fibroids. Descriptive statistics, chi-square analysis, and logistic regression were used for data analysis.
Results: The study recruited 452 participants. Participants with fibroids had higher serum LDL and HDL cholesterol (71.4% and 81.3%, respectively) than those without fibroids (28.0% and 18.7%, respectively). Additionally, triglycerides were shown to modestly increase in fibroid individuals compared to those without. On the other hand, there was a significant (p value <
0.05) 2.1 chance of having UF for those with higher LDL cholesterol. Patients who had higher
serum HDL cholesterol were also 2.4 times more likely to have uterine fibroids. Furthermore, Use
of polished nails and lipstick, poor physical excessing, older reproductive age and education at
secondary school level were the most sociodemographic factors significantly (p < 0.05)
associating to uterine fibroid among study participants.
Conclusions: The present study found that participants with uterine fibroid had elevated serum cholesterol compared to those without fibroid. Also, there was a significant association between rise of serum cholesterol and presence of uterine fibroid. Furthermore, women at later reproductive age, those with poor physical excessing, and those educated at secondary school level were the risk to present with uterine fibroid.
Description
Dissertation submitted to the Faculty of Medicine in partial fulfillment of the requirements for the degree of Master of Medicine in Obstetrics and Gynecology of Kairuki University
Keywords
serum lipid profile, uterine fibroid, infertility
Citation
Shirima, Devotha A., 2024. Association of lipid profile with uterine fibroid among women attending gynecological clinic in selected hospitals Dar es Salaam Tanzania from April to June 2024. Dissertation. Kairuki university