A novel isoflavonoid from Millettia puguensis

dc.contributor.author	Moshi, Mainen J.
dc.date.accessioned	2023-08-14T06:50:37Z
dc.date.available	2023-08-14T06:50:37Z
dc.date.issued	2006
dc.description.abstract	From the roots of Millettia puguensis (Leguminosae), a novel iso- flavonoid (5), 2¢-methoxy-4¢,5¢-methylenedioxy-7,8-[2-(1-me-thylethenyl)furo]isoflavone, and four known compounds, i. e., lu-peol (1), (-)-maackiain (2), 6,7-dimethoxy-3¢,4¢-methylenedioxy-isoflavone (3) and 7,2¢-dimethoxy-4¢,5¢-ylenedioxyisofla-vone (4) were isolated and identified by 1H-, 13C-NMRand massspectroscopy. All compounds were evaluated for their antiproto-zoal and cytotoxic activities, but only a moderate antileishmanialactivity was observed for compound 3 (IC 50 = 32mM againstLeishmania infantum), and a moderate cytotoxicity for com-pound 2 (IC 50 = 43 mM on MRC-5 cells)	en_US
dc.identifier.citation	Kapingu, M.C., Mbwambo, Z.H., Moshi, M.J., Magadula, J.J., Cos, P., Berghe, D.V., Maes, L., Theunis, M., Apers, S., Pieters, L. and Vlietinck, A., 2006. A novel isoflavonoid from Millettia puguensis. Planta medica, 72(14), pp.1341-1343.	en_US
dc.identifier.other	DOI: 10.1055/s-2006-951689
dc.identifier.uri	http://hdl.handle.net/123456789/1135
dc.language.iso	en	en_US
dc.publisher	Planta medica	en_US
dc.subject	Novel	en_US
dc.subject	Millettia puguensis	en_US
dc.subject	Isoflavonoid	en_US
dc.title	A novel isoflavonoid from Millettia puguensis	en_US
dc.type	Article	en_US