Homo sapiens Duffy antigen/Receptor for chemokines (DARC) gene, DARC-Fya allele, partial cds

dc.contributor.author	Mgone, Charles S.
dc.date.accessioned	2020-10-22T08:34:59Z
dc.date.available	2020-10-22T08:34:59Z
dc.date.issued	1998
dc.description.abstract	This sequence has a T to C point mutation at position -46 in the promoter region. Previous studies (Tournamille, C et al. Nature Genetics 10:224-228, 1995) have shown that this nucleotide change blocks Duffy (Fy) antigen expression in erythroid lineage cells and would therefore confer resistance to Plasmodium vivax infection in Africans and African Americans. Tournamille and others have shown that this mutation is consistently linked to the nucleotide sequence encoding the Fyb serological epitope (nucleotide 625A). The submitted sequence is the first report of FY -46C linked to the nucleotide sequence encoding the Fya serological epitope (nucleotide 625G). At the time of this submission this allelic sequence has been observed in 23/523 study subjects who reside in a P. vivax endemic region (South Wosera,Papua New Guinea).	en_US
dc.identifier.citation	Mgone, C.S. et al 1998Homo sapiens Duffy antigen/Receptor for chemokines (DARC) gene, DARC-Fya allele, partial cds	en_US
dc.identifier.uri	https://www.researchgate.net/publication/309925641
dc.identifier.uri	http://hdl.handle.net/123456789/689
dc.language.iso	en	en_US
dc.publisher	Thermo Fisher scientific	en_US
dc.subject	Receptor for chemokines gene	en_US
dc.title	Homo sapiens Duffy antigen/Receptor for chemokines (DARC) gene, DARC-Fya allele, partial cds	en_US
dc.type	Article	en_US

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