Seroprevalences of Helicobacter pylori infection and chronic atrophic gastritis in the United Republic of Tanzania and the Dominican Republic
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Date
2004-07
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Environmental Health and Preventive Medicine
Abstract
Objective: The aim of this survey was to compare the seroprevalences of Helicobacter Pylori (H.
pylori) and chronic atrophic gastritis (CAG) in Tanzania and the Dominican Republic, both of which
are tropical countries, and thereafter compare the prevalences in Tanzania and the Dominican Republic
with prevalences from our previous studies done in Japan (1991) and China (1996/97).
Methods: Community-based study in which 573 inhabitants of Tanzania and 1,215 inhabitants of
the Dominican Republic answered detailed questionnaires on upper digestive tract diseases, and then
underwent screening for gastric cancer by serum pepsinogen and testing for antibody to H. pylori.
Results: After adjusting to the ‘Age-Standardized Rate’ (ASR) using the world population in
1995, the seroprevalences of H. pylori infection in male and female subjects for Tanzania (m=85.3% &
f=88.2%) were very high compared to those for the Dominican Republic (m=63.5% & f=62.4%) and
Japan (m=62.0% & f=46.8%), and similar to those of China (m=78.0% & f=77.3%). Also, the age-
standardized prevalences of CAG in males and females for Tanzania (m=0.237 & f=0.458) were higher
than those of the Dominican Republic (m=0.168 & f=0.211) and China (m=0.111 & f=0.107) and
compared well with those of Japan (m=0.266 & f=0.352).
Conclusions: Although Tanzania and the Dominican Republic are both developing countries,
Tanzania had a very high age-standardized prevalence of H. pylori and CAG compared to that of the
Dominican Republic, which showed a trend similar to that of Japan.
Key words: Helicobacter pylori, chronic atrophic gastritis, gastric cancer, Tanzania, Dominican Republic
Description
Keywords
Helicobacter pylori, Chronic atrophic gastrit, Tanzania
Citation
Aoki, K., Kihaile, P.E., Castro, M., Disla, M., Nyambo, T.B. and Misumi, J., 2004. Seroprevalences of Helicobacter pylori infection and chronic atrophic gastritis in the United Republic of Tanzania and the Dominican Republic. Environmental Health and Preventive Medicine, 9(4), pp.170-175.