Seroprevalences of Helicobacter pylori infection and chronic atrophic gastritis in the United Republic of Tanzania and the Dominican Republic

dc.contributor.authorNyambo, Thomas B.
dc.date.accessioned2023-09-18T07:25:03Z
dc.date.available2023-09-18T07:25:03Z
dc.date.issued2004-07
dc.description.abstractObjective: The aim of this survey was to compare the seroprevalences of Helicobacter Pylori (H. pylori) and chronic atrophic gastritis (CAG) in Tanzania and the Dominican Republic, both of which are tropical countries, and thereafter compare the prevalences in Tanzania and the Dominican Republic with prevalences from our previous studies done in Japan (1991) and China (1996/97). Methods: Community-based study in which 573 inhabitants of Tanzania and 1,215 inhabitants of the Dominican Republic answered detailed questionnaires on upper digestive tract diseases, and then underwent screening for gastric cancer by serum pepsinogen and testing for antibody to H. pylori. Results: After adjusting to the ‘Age-Standardized Rate’ (ASR) using the world population in 1995, the seroprevalences of H. pylori infection in male and female subjects for Tanzania (m=85.3% & f=88.2%) were very high compared to those for the Dominican Republic (m=63.5% & f=62.4%) and Japan (m=62.0% & f=46.8%), and similar to those of China (m=78.0% & f=77.3%). Also, the age- standardized prevalences of CAG in males and females for Tanzania (m=0.237 & f=0.458) were higher than those of the Dominican Republic (m=0.168 & f=0.211) and China (m=0.111 & f=0.107) and compared well with those of Japan (m=0.266 & f=0.352). Conclusions: Although Tanzania and the Dominican Republic are both developing countries, Tanzania had a very high age-standardized prevalence of H. pylori and CAG compared to that of the Dominican Republic, which showed a trend similar to that of Japan. Key words: Helicobacter pylori, chronic atrophic gastritis, gastric cancer, Tanzania, Dominican Republicen_US
dc.identifier.citationAoki, K., Kihaile, P.E., Castro, M., Disla, M., Nyambo, T.B. and Misumi, J., 2004. Seroprevalences of Helicobacter pylori infection and chronic atrophic gastritis in the United Republic of Tanzania and the Dominican Republic. Environmental Health and Preventive Medicine, 9(4), pp.170-175.en_US
dc.identifier.otherhttps://doi.org/10.1265/ehpm.9.170
dc.identifier.urihttp://hdl.handle.net/123456789/1185
dc.language.isoenen_US
dc.publisherEnvironmental Health and Preventive Medicineen_US
dc.subjectHelicobacter pylorien_US
dc.subjectChronic atrophic gastriten_US
dc.subjectTanzaniaen_US
dc.titleSeroprevalences of Helicobacter pylori infection and chronic atrophic gastritis in the United Republic of Tanzania and the Dominican Republicen_US
dc.typeArticleen_US

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