Cardiac changes among pregnant women with pre-eclampsia and associated fetal – maternal outcomes at Mnazi mmoja tertiary hospital – Zanzibar
| dc.contributor.author | Omar, Aysha M. | |
| dc.date.accessioned | 2025-01-30T10:38:12Z | |
| dc.date.available | 2025-01-30T10:38:12Z | |
| dc.date.issued | 2024 | |
| dc.description | A dissertation submitted to the Department of Obstetrics and Gynaecology School as partial fulfillment of the requirements for the award of the master’s degree of Obstetrics and Gynaecology at Kairuki University on 2024 | |
| dc.description.abstract | Background: Pre-eclampsia, a pregnancy complication marked by high blood pressure and protein in urine, can lead to heart problems in mothers. This study investigated the link between echocardiographic abnormalities (identified through echocardiography) and maternal and fetal outcomes in Pre-eclamptic patients in Zanzibar. Methods: A prospective cohort study enrolled 151 pregnant women with pre-eclampsia. Social-demographic characteristics of study participants were collected using a pre-designed questionnaire. Echocardiographic (ECHO) studies were performed among participants to determine cardiac changes due to preeclampsia. Participants were monitored up to delivery to determine the immediate maternal and fetal outcome. Data was analyzed using Statistical Package for Social Sciences (SPSS). Categorical variables were presented in frequency and respective percentages. Association between ECHO changes and severity of Pre-eclampsia, maternal and fetal outcome were assessed using Chi-square test. A p-value of less or equal to 0.05 was regarded as statistically significant. Results: A total of 151 participants were enrolled in the study. Among participants, 101(67.5%) had severe form of Pre-eclampsia. Additionally, 80 (53%) of study participants had abnormal ECHO findings with left ventricular hypertrophy the most frequent finding (22%). There were a significant association between abnormal ECHO findings and severity of Preeclampsia (p<0.001). Furthermore abnormal ECHO findings was associated with adverse maternal and fetal/ neonatal outcome; (p<0.001), and (p=0.05) respectively. Conclusion: In this study, the majority of patients with Pre-eclampsia had abnormal ECHO findings, which was associated with severity of the disease, maternal and fetal/neonatal outcomes. To improve maternal and neonatal survival, routine cardiac screening using echocardiogram among pregnant mothers at risk for early appropriate treatment should be considered. In this study, the majority of patients with Pre-eclampsia had abnormal ECHO findings, which was associated with severity of the disease, maternal and fetal/neonatal outcomes. | |
| dc.identifier.citation | Omar, Aysha M., 2024. Cardiac changes among pregnant women with pre-eclampsia and associated fetal – maternal outcomes at Mnazi mmoja tertiary hospital – Zanzibar. Kairuki University | |
| dc.identifier.uri | http://kuir.ku.ac.tz:4000/handle/123456789/1470 | |
| dc.language.iso | en | |
| dc.publisher | Kairuki University | |
| dc.subject | Pre-eclampsia | |
| dc.subject | ECHO | |
| dc.subject | Zanzibar | |
| dc.title | Cardiac changes among pregnant women with pre-eclampsia and associated fetal – maternal outcomes at Mnazi mmoja tertiary hospital – Zanzibar | |
| dc.type | Thesis |