Brine shrimp lethality of a glutarimide alkaloid from Croton sylvaticus Hochst

dc.contributor.authorMoshi, Mainen J.
dc.date.accessioned2023-08-11T05:40:19Z
dc.date.available2023-08-11T05:40:19Z
dc.date.issued2005-04
dc.description.abstractCytotoxic properties of pure compounds from the leaves of roto on sylvaticus (Euphorbiaceae) against brine shrimp (Artemia salina) larvae were investigated. A glutarimide alkaloid, julocrotine (1) showed'very high cytotoxic activity with a LCs0 (95 % CI) value of 0.074 (0.052-0.105) pglml when tested in vitro while lupeol (2) and penduliflaworisin (3) were inactive in brine shrimp lethality test. The structures of the isolated compounds were determined by modern spectroscopic methods.en_US
dc.identifier.citationKapingu, M.C., Mbwambo, Z.H., Moshi, M.J. and Magadula, J.J., 2005. Brine shrimp lethality of a glutarimide alkaloid from Croton sylvaticus Hochst. East and Central African Journal of Pharmaceutical Sciences, 8(1), pp.3-5.en_US
dc.identifier.other10.4314/ecajps.v8i1.9716
dc.identifier.urihttp://hdl.handle.net/123456789/1088
dc.language.isoenen_US
dc.publisherEast and Central African Journal of Pharmaceutical Sciencesen_US
dc.subjectCroton sylvaticusen_US
dc.subjectEuphorbiaceaeen_US
dc.subjectJulocrotineen_US
dc.titleBrine shrimp lethality of a glutarimide alkaloid from Croton sylvaticus Hochsten_US
dc.typeArticleen_US

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