Brine shrimp lethality of a glutarimide alkaloid from Croton sylvaticus Hochst
dc.contributor.author | Moshi, Mainen J. | |
dc.date.accessioned | 2023-08-11T05:40:19Z | |
dc.date.available | 2023-08-11T05:40:19Z | |
dc.date.issued | 2005-04 | |
dc.description.abstract | Cytotoxic properties of pure compounds from the leaves of roto on sylvaticus (Euphorbiaceae) against brine shrimp (Artemia salina) larvae were investigated. A glutarimide alkaloid, julocrotine (1) showed'very high cytotoxic activity with a LCs0 (95 % CI) value of 0.074 (0.052-0.105) pglml when tested in vitro while lupeol (2) and penduliflaworisin (3) were inactive in brine shrimp lethality test. The structures of the isolated compounds were determined by modern spectroscopic methods. | en_US |
dc.identifier.citation | Kapingu, M.C., Mbwambo, Z.H., Moshi, M.J. and Magadula, J.J., 2005. Brine shrimp lethality of a glutarimide alkaloid from Croton sylvaticus Hochst. East and Central African Journal of Pharmaceutical Sciences, 8(1), pp.3-5. | en_US |
dc.identifier.other | 10.4314/ecajps.v8i1.9716 | |
dc.identifier.uri | http://hdl.handle.net/123456789/1088 | |
dc.language.iso | en | en_US |
dc.publisher | East and Central African Journal of Pharmaceutical Sciences | en_US |
dc.subject | Croton sylvaticus | en_US |
dc.subject | Euphorbiaceae | en_US |
dc.subject | Julocrotine | en_US |
dc.title | Brine shrimp lethality of a glutarimide alkaloid from Croton sylvaticus Hochst | en_US |
dc.type | Article | en_US |
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