Asymptomatic hypoglycemia among pretermnewborns: A cross-sectional analysis
| dc.contributor.author | Kalabamu, Florence S. | |
| dc.contributor.author | Fataki, Maulidi R. | |
| dc.date.accessioned | 2024-05-07T12:03:40Z | |
| dc.date.available | 2024-05-07T12:03:40Z | |
| dc.date.issued | 2024-04-30 | |
| dc.description.abstract | Background: Hypoglycemia is the commonest metabolic abnormality encountered in newborns. Besides, there is a growing body of evidence that links the causes of early neonatal mortality to neonatal hypoglycemia in Tanzania. However exact factors associated with asymptomatic hypoglycemia in preterm newborns are not known. Objective: Toassess factors associated with asymptomatic hypoglycemia among preterm newborns. Materials and methods Across sectional, analytical hospital- based study was carried out at Dar es salaam public regional referral hospitals. Preterm newborns with asymptomatic hypoglycemia were the target population. Data on demographic and clinical characteristics of preterm newborns andtheir mothers were collected and analyzed using Epi-Info™ software version 7.4. Main data analysis was done by applying a multivariable binary logistic regression model with neonatal random glycaemia coded in a binary fashion at a cut-off point of 2.6 mmol/L. An α level of 5% was used as a limit of type I error. Results: Werecruited and analysed 217 preterm newborns within 6–24 hours post-delivery. Male: Female =1.1:1 (females n = 105, 48.4%). Median glycemic level was 2.6 (IQR; 2.1–3.9) mmol/L. Median gestational age at delivery was 33 (IQR: 30–35) weeks. Breastfeeding within 1st hour post-delivery was a statistically significant factor against glycemic level associated with hypoglycemia (OR; 0.123, 95%-CI; 0.052–0.287) in a fitted multivariable logistic regression model. Conclusion: About half of all preterm newborns studied had glycemic values in a statistical range associated with hypoglycemia. Exclusive breast feeding within 1st hour post-delivery was associated with glycemic levels protective from risk of asymptomatic neonatal hypoglycemia. Recommendations: Exclusive breastfeeding practices within 1st hour post-delivery may need to be emphasized to all expectant mothers in order to avoid potential risk of asymptomatic hypoglycemia in preterm newborns. | en_US |
| dc.identifier.citation | Salum, S.S., Kalabamu, F.S., Fataki, M.R., Omary, S.A., Mohammed, U.H., Kizwi, H.A. and Leshabari, K.M., 2024. Asymptomatic hypoglycemia among preterm newborns: A cross-sectional analysis. PloS one, 19(4), p.e0301803. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/1353 | |
| dc.language.iso | en | en_US |
| dc.publisher | Plos One | en_US |
| dc.subject | Hypoglycemia | en_US |
| dc.subject | Preterm newborn | en_US |
| dc.title | Asymptomatic hypoglycemia among pretermnewborns: A cross-sectional analysis | en_US |
| dc.type | Article | en_US |