Determining cutaneous markers of dyslipidemia among hiv seropositive patients on antiretroviral therapy attending care and treatment clinics in Dar es Salaam
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Date
2024
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kairuki University
Abstract
Background: The prevalence of ischaemic heart disease (IHD) in Sub-Saharan Africa has been on the rise among people living with HIV. HIV infection and antiretroviral drugs (ARTs) are both associated with dyslipidemia.
Objective: This study aimed to determine the prevalence of cutaneous markers of dyslipidemia and associated factors among HIV seropositive on ARTs attending CTCs in Dares Salaam.
Method: A descriptive cross-sectional study among HIV seropositive individuals aged 18 years and above were enrolled at Kairuki Hospital and Mwananyamala Regional Referral Hospital, from February to July 2024, and a 100% response rate was obtained. The diagnosis of cutaneous markers of
dyslipidemia was based on physical examination (Visual inspection by naked eye keenly looking for cutaneous markers). A fasting blood sample was obtained for serum markers of dyslipidemia
Results: The study recruited 305 people, 21 persons were excluded due to missing data, and a total of 284 were analysed with a response rate of 100%. The mean age of participants was 46.7±10.9, and 182(64.1%). The mean BMI was 26.2±5.5, with 80(28.2%) were overweight. Fifty per cent of participants were on ART for 10 years or more. A total of 17(5.9%) participants were found to have cutaneous markers of dyslipidemia. No association was found between alcohol consumption, cigarette smoking, and other predictors of dyslipidemia.
Conclusion: This study found the prevalence of cutaneous markers of dyslipidemia; henceforth heralding the need of incorporating lipid screening as a component of care among HIV seropositive individuals on ARTs, for reducing mortality and morbidity.
Description
A dissertation submitted in partial fulfilment of the requirements for the degree of
Masters of Medicine (MMED) in Internal Medicine 2024
Keywords
HIV seropositive, ARTs, ischaemic heart disease
Citation
Mlangwa, Mhina E., 2024. Determining cutaneous markers of dyslipidemia among HIV seropositive patients on antiretroviral therapy attending care and treatment clinics in Dar es Salaam. Kairuki University