Determining cutaneous markers of dyslipidemia among hiv seropositive patients on antiretroviral therapy attending care and treatment clinics in Dar es Salaam
| dc.contributor.author | Mlangwa, Mhina E. | |
| dc.date.accessioned | 2025-01-30T10:37:17Z | |
| dc.date.available | 2025-01-30T10:37:17Z | |
| dc.date.issued | 2024 | |
| dc.description | A dissertation submitted in partial fulfilment of the requirements for the degree of Masters of Medicine (MMED) in Internal Medicine 2024 | |
| dc.description.abstract | Background: The prevalence of ischaemic heart disease (IHD) in Sub-Saharan Africa has been on the rise among people living with HIV. HIV infection and antiretroviral drugs (ARTs) are both associated with dyslipidemia. Objective: This study aimed to determine the prevalence of cutaneous markers of dyslipidemia and associated factors among HIV seropositive on ARTs attending CTCs in Dares Salaam. Method: A descriptive cross-sectional study among HIV seropositive individuals aged 18 years and above were enrolled at Kairuki Hospital and Mwananyamala Regional Referral Hospital, from February to July 2024, and a 100% response rate was obtained. The diagnosis of cutaneous markers of dyslipidemia was based on physical examination (Visual inspection by naked eye keenly looking for cutaneous markers). A fasting blood sample was obtained for serum markers of dyslipidemia Results: The study recruited 305 people, 21 persons were excluded due to missing data, and a total of 284 were analysed with a response rate of 100%. The mean age of participants was 46.7±10.9, and 182(64.1%). The mean BMI was 26.2±5.5, with 80(28.2%) were overweight. Fifty per cent of participants were on ART for 10 years or more. A total of 17(5.9%) participants were found to have cutaneous markers of dyslipidemia. No association was found between alcohol consumption, cigarette smoking, and other predictors of dyslipidemia. Conclusion: This study found the prevalence of cutaneous markers of dyslipidemia; henceforth heralding the need of incorporating lipid screening as a component of care among HIV seropositive individuals on ARTs, for reducing mortality and morbidity. | |
| dc.identifier.citation | Mlangwa, Mhina E., 2024. Determining cutaneous markers of dyslipidemia among HIV seropositive patients on antiretroviral therapy attending care and treatment clinics in Dar es Salaam. Kairuki University | |
| dc.identifier.uri | http://kuir.ku.ac.tz:4000/handle/123456789/1469 | |
| dc.language.iso | en | |
| dc.publisher | Kairuki University | |
| dc.subject | HIV seropositive | |
| dc.subject | ARTs | |
| dc.subject | ischaemic heart disease | |
| dc.title | Determining cutaneous markers of dyslipidemia among hiv seropositive patients on antiretroviral therapy attending care and treatment clinics in Dar es Salaam | |
| dc.type | Thesis |