Aetiology, antimicrobial susceptibility and predictors of urinary tract infection among febrile under-fives at Muhimbili National Hospital, Dar es Salaam-Tanzania
Loading...
Date
2013
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
African Journal of Microbiology Research
Abstract
Urinary tract infection (UTI) is a common cause of fever in children and contributes to morbidity and
mortality. This study aimed at determining prevalence, aetiology and antimicrobial susceptibility pattern
of the isolates at Muhimbili National Hospital (MNH), Dar es Salaam- Tanzania. Demographic data were
collected using a pretested questionnaire. 382 febrile children below five years admitted in the general
paediatric wards were recruited. Urine specimens were obtained for urinalysis, culture and antimicrobial
sensitivity testing. UTI was detected in 16.8% (64/382). Children who presented prolonged duration of
fever (7 days or longer) were more likely to have UTI (p< 0.01). Duration of fever, positive leukocyte and
nitrite tests were independent predictors of UTI. Isolated bacteria included Escherichia coli (39.1%),
Klebsiella spp (31.2%), Staphylococcus epidermidis (6.2%), Staphylococcus aureus (4.7%) and
Pseudomonas aeruginosa (4.7%). We observed high resistance of the isolated uropathogens to
ampicillin (79.9%), co-trimoxazole (89%) and clavulanate-amoxillin (70.3%). Amikacin had the least
resistance (12.5%) from the isolated pathogens.
Description
Keywords
Urinary tract infection, Uropathogens, Antimicrobial susceptibility
Citation
Francis, F., Joel, M.F., Maulidi, F. and Samuel, Y.M., 2013. Aetiology, antimicrobial susceptibility and predictors of urinary tract infection among febrile under-fives at Muhimbili National Hospital, Dar es Salaam-Tanzania. African journal of microbiology research, 7(12), pp.1029-1034.