An unusual presentation of placental malaria: a single persisting nidus of sequestered parasites
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Date
2007
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Human pathology
Abstract
Summary:
Placental malaria caused by Plasmodium falciparum is a public health concern in tropical countries. Peripheral blood smears to detect placental malaria are often negative, and recrudescences are common during pregnancy. We erformed placental histology on a series of firsttime mothers delivering in an area endemic for P falciparum. A single
nidus of malaria-infected erythrocytes was identified by placental histology in a single intervillous space from a woman who had no other evidence of peripheral or placental blood parasitemia. This finding suggests ring stage–infected erythrocytes sequester in vivo, or Pfalciparum can persist as a dormant blood stage form.
Description
Keywords
Malaria-falciparum, Pregnancy, Placenta
Citation
Muehlenbachs, A., Mutabingwa, T.K., Fried, M. and Duffy, P.E., 2007. An unusual presentation of placental malaria: a single persisting nidus of sequestered parasites. Human pathology, 38(3), pp.520-523.