Plasmodium falciparum histidine-rich protein-2 (pHRP-2) is a cerebrospinal fluid (CSF) biomarker for cerebral malaria (CM)
| dc.contributor.author | Mwaikambo, Esther D. | |
| dc.contributor.author | Kalabamu, Florence S. | |
| dc.date.accessioned | 2020-10-22T13:14:46Z | |
| dc.date.available | 2020-10-22T13:14:46Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | Abstract Background: Cerebral malaria (CM) causes a rapidly developing comatose state and remains a major contributor to morbidity and mortality in malaria-endemic regions. CM may be diagnosed during life by the presence of Plasmodium/INS; falciparum parasitemia, clinical assessment and retinal changes. The plasma level of pHRP-2, a malaria histidine- and alanine-rich protein, identifies children with histologically confirmed or retinopathy-positive CM with high specificity and sensitivity. We sought to determine whether pHRP-2 levels in the CSF were detectable in CM cases | en_US |
| dc.identifier.citation | Thakur, K.T., Mikita, K., Piera, K., Pardo-Villamizar, C., Weinberg, J.B., Anstey, N.M., Mukemba, J., Florence, S., Mwaikambo, E.D., Granger, D.L. and Sullivan, D., 2013. Plasmodium falciparum histidine-rich protein-2 (pHRP-2) is a cerebrospinal fluid (CSF) biomarker for cerebral malaria (CM). Journal of the Neurological Sciences, 333, p.e697. | en_US |
| dc.identifier.other | doi.org/10.1016/j.jns.2013.07.2409 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/701 | |
| dc.language.iso | en | en_US |
| dc.publisher | Journal of the Neurological Sciences | en_US |
| dc.subject | Plasmodium | en_US |
| dc.subject | Falciparum | en_US |
| dc.subject | Celebral Malaria | en_US |
| dc.title | Plasmodium falciparum histidine-rich protein-2 (pHRP-2) is a cerebrospinal fluid (CSF) biomarker for cerebral malaria (CM) | en_US |
| dc.type | Article | en_US |
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