Cytotoxic screening of some Tanzania medicinal plants. East and Central African Journal of Pharmaceutical Sciences

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dc.contributor.authorMoshi, Mainen J.
dc.date.accessioned2023-08-11T05:38:36Z
dc.date.available2023-08-11T05:38:36Z
dc.date.issued2003
dc.description.abstractRauvolfia caffra reduced cell proliferation to 50% or more of the three cell lines. Albizia harveyi showed a significant cytotoxic activity on the RT-4 cell line (percentage survival 23%) at 10pgIml. It showed a weak cytotoxic activitv on the HT-29 cell line. Dalbergia nitidula. showed a weak cytotoxic activity with percentage death of the RT-4 and HT-29 cell lines of 39 and 34%, respectively, at the 10 pghnl level. These results show that 19 (95%) of the plant extracts tested are non-toxic. One plant (5%), Albizia harveyi showed cytotoxic activity on one of the cell lines used, which was in agreement with the accepted detection level of biological activity by chance. Bioassay guided fractionation of the plant extracts to identify active compound (s) is suggested.en_US
dc.identifier.citationMoshi, M.J., Kamuhabwa, A., Mbwambo, Z. and De Witte, P., 2003. Cytotoxic screening of some Tanzania medicinal plants. East and Central African Journal of Pharmaceutical Sciences, 6(3), pp.52-56.en_US
dc.identifier.otherhttps://www.ajol.info/index.php/ecajps/article/view/9700
dc.identifier.urihttp://hdl.handle.net/123456789/1087
dc.language.isoenen_US
dc.publisherEast and Central African Journal of Pharmaceutical Sciencesen_US
dc.subjectCytotoxicityen_US
dc.subjectHuman cancer cell linesen_US
dc.subjectPlant extractsen_US
dc.titleCytotoxic screening of some Tanzania medicinal plants. East and Central African Journal of Pharmaceutical Sciencesen_US
dc.typeArticleen_US

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