Cleistenolide and cleistodienol: novel bioactive constituents of cleistochlamys kirkii

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dc.contributor.authorMoshi, Mainen J.
dc.date.accessioned2023-08-14T11:27:16Z
dc.date.available2023-08-14T11:27:16Z
dc.date.issued2007
dc.description.abstract(-)-5-Acetoxy-6-(1-benzoyloxy-2-acetoxyethyl)-pyr-3-en-2-one (cleistenolide) and (-)-2,6-diacetoxy-5-hydroxy-cyclohex-3-enylidenemethyl benzoate (cleistodienol) were isolated as novel antimicrobial and cytotoxic constituents of Cleistochlamys kirkii (Annonaceae), together with (Z)-(+)-5-(2,3-dihydroxy-propylidene)-5H-furan-2-one and its acetyl and benzoyl derivatives, (-)-1,6-desoxy-β-senepoxide, pinocembrin and polycarpol. Structural determination was achieved based on spectroscopic and other physical data. The structure of cleistenolide was confirmed by single crystal X-ray crystallographic analysis.en_US
dc.identifier.citationSamwel, S., Mdachi, S.J., Nkunya, M.H., Irungu, B.N., Moshi, M.J., Moulton, B. and Luisi, B.S., 2007. Cleistenolide and cleistodienol: Novel bioactive constituents of Cleistochlamys kirkii. Natural Product Communications, 2(7), p.1934578X0700200706.en_US
dc.identifier.otherhttps://doi.org/10.1177/1934578X0700200706
dc.identifier.urihttp://hdl.handle.net/123456789/1137
dc.language.isoenen_US
dc.publisherNatural Product Communicationsen_US
dc.subjectCleistochlamys kirkiien_US
dc.subjectAnnonaceaeen_US
dc.subjectHeptenolidesen_US
dc.titleCleistenolide and cleistodienol: novel bioactive constituents of cleistochlamys kirkiien_US
dc.typeArticleen_US

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