Zinc as an adjunct for childhood pneumonia – interpreting early results

Fataki, Maulidi R.

Zinc as an adjunct for childhood pneumonia – interpreting early results

dc.contributor.author	Fataki, Maulidi R.
dc.date.accessioned	2020-02-28T05:06:18Z
dc.date.available	2020-02-28T05:06:18Z
dc.date.issued	2008
dc.description.abstract	ABSTRACT Zinc supplementation has been consistently shown to reduce the incidence of childhood pneumonia, but its effect on the course of pneumonia when administered as an adjunct to antibiotic therapy is still unclear. Three trials published to date have shown mixed results, and a recent trial from India raises the possibility that zinc may be detrimental in some circumstances. Study sites and designs differ, particularly in the timing of zinc treatment and in determining recovery from pneumonia, which can explain the differences in study findings. Serum zinc concentrations are unreliable indicators of zinc status, particularly during acute infectious illnesses. Subgroup analyses, especially using serum zinc levels, must be cautioned against. Future studies are needed that are large enough to be sufficiently powered to accommodate larger treatment failure rates, an issue that ongoing trials will hopefully address.	en_US
dc.identifier.citation	Natchu, U.C.M., Fataki, M.R. and Fawzi, W.W., 2008. Zinc as an adjunct for childhood pneumonia–interpreting early results. Nutrition reviews, 66(7), pp.398-405	en_US
dc.identifier.other	doi.org/10.1111/j.1753-4887.2008.00049.x
dc.identifier.uri	http://hdl.handle.net/123456789/281
dc.language.iso	en	en_US
dc.publisher	Nutrition reviews	en_US
dc.subject	Acute lower respiratory infection	en_US
dc.subject	Childhood pneumonia	en_US
dc.subject	Zinc	en_US
dc.title	Zinc as an adjunct for childhood pneumonia – interpreting early results	en_US
dc.type	Article	en_US