Reports on plasmodium falciparum histidine rich protein 2/3 gene deletions among african countries between January 2010 and december 2021 employed different methodological approaches: A systematic review
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Date
2023-04-01
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Publisher
International Journal of Tropical Disease and Health
Abstract
Background: Plasmodium falciparum histidine rich protein 2/3 gene deletions (Pfhrp2/3gd)
threatens usefulness of mRDT in diagnosing malaria cases. This review was performed to assess
the methods used to report findings on those deletions between January 2010 and December 2021.
Methods: Present search was performed using Medline, Google Scholar and PubMed.
Results: Out of 94 articles identified, 19% (n=18) were included. Reviewed articles varied in
methods employed to report those deletions.
Conclusion: Methodological approaches for the Reports between January 2010 and December
2021 on Pfhrp2/3gd are varying and this implies that the findings may not be generalized.
Prospective studies aiming at assessing Pfhrp2/3gd need to consider WHO guidelines since such
studies are important in assessing the magnitude of Pfhrp2/3gd and therefore provide information
towards formulating and change of policies aiming at malaria control.
Description
Keywords
Plasmodium falciparum, Gene, Histidine
Citation
Sylvester, B. (2023). Reports on Plasmodium falciparum Histidine Rich Protein 2/3 Gene Deletions among African Countries between January 2010 and December 2021 Employed Different Methodological Approaches: A Systematic Review. International Journal of TROPICAL DISEASE & Health, 44(6), 1–6. https://doi.org/10.9734/ijtdh/2023/v44i61409