Single breath assessment of bronchial responsiveness: A Comparison with the astograph method

dc.contributor.authorMashalla, Yohana J.
dc.date.accessioned2021-10-28T10:47:38Z
dc.date.available2021-10-28T10:47:38Z
dc.date.issued1991-12-12
dc.description.abstractBronchial responsiveness to inhaled doubling concentrations of acetylcholine using the astograph and single breathtechniques was assessed im 7 males and 11 females <meanage 22.7, SD==2,05 and 21.2, SD== 1.11},ears tbr male and femule respectivcly) healthy volunteers. Eleven (61%> of the subjects had neither a historyof allcrgy nor whcczcs. Five<28%)haclallcrgic rhinitis and two (11%)had asthma. Seven (64%)ef the normal subjects, all asthmatic and sulijects with allergic rhinitis responded to inhaled acetylcholine. Respiratery conductance (Grs}and the one second ft)rsedexpired volume (FEVD expressed as percentages of thc baselinevalues were compared on a semilogarithmic scalc against cumulativc dosc. In most sub.iccts thc pattern of the curves showed c]ose similarities in the two methods. 'I'hebronchial sensitivity i.e.minimum cumulativc dosc of acctylcholinc justsuMcient to start a fallin the FEVL and Grs(C.i,,s and C.,t.Arespectively), showcd good corrclation (r=O,750,P<O,Ol), Thc rcsults indicatethat bronchial responsiveness can be reliably assessed using the simple single breath methed as well as the more complex astograph mcthod.en_US
dc.identifier.citationMASHALLA, Y.J., TOKUI, N. and KIDO, M., 1991. Single Breath Assessment of Bronchial Responsiveness: A Comparison with the Astograph Method. Journal of UOEH, 13(1), pp.1-11.en_US
dc.identifier.urihttps://www.jstage.jst.go.jp/article/juoeh/13/1/13_KJ00002572295/_pdf/-char/ja
dc.identifier.urihttp://hdl.handle.net/123456789/850
dc.language.isoenen_US
dc.publisherJournal of UOEHen_US
dc.subjectRespiratory conductanceen_US
dc.subjectAstographen_US
dc.subjectBronchial sensitivityen_US
dc.titleSingle breath assessment of bronchial responsiveness: A Comparison with the astograph methoden_US
dc.typeArticleen_US

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