Testing beyond ethnomedical claims: brine shrimp lethality of some Tanzanian plants

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dc.contributor.authorMoshi, Mainen J.
dc.date.accessioned2023-08-11T06:04:42Z
dc.date.available2023-08-11T06:04:42Z
dc.date.issued2004
dc.description.abstractExtracts of 34 plants that are traditionally used for the treatment of different diseases exhibited various degrees of toxicity on brine shrimp. The concentration killing 50% (LC50) of the shrimps was below 50 μg/ml for 14 (41.2%), 50–100 μ g/ml for 10 (29.4%), and greater than 100 μg/ml for 10 (29.4%) of the plants, respectively. Dalbergia nitidula (LC50 0.87 μg/ml), Ozoroa insignis (LC50 2.21 μg/ml), Markhamia obtusifolia (LC50 8.94 μg/ml), Ximenia caffra (LC50 11.25 μg/ml),Croton macrostachys (LC50 13.40 μg/ml), and Mormodica calantha (LC50 19.38 μg/ml) were the most toxic. The results indicate the possibility that some of the plant extracts may be toxic or contain useful cytotoxic compounds, which was not reported by the traditional healers.en_US
dc.identifier.citationMoshi, M.J., Cosam, J.C., Mbwambo, Z.H., Kapingu, M. and Nkunya, M.H., 2004. Testing beyond ethnomedical claims: brine shrimp lethality of some Tanzanian plants. Pharmaceutical Biology, 42(7), pp.547-551.en_US
dc.identifier.otherhttps://doi.org/10.3109/13880200490897920
dc.identifier.urihttp://hdl.handle.net/123456789/1102
dc.language.isoenen_US
dc.publisherPharmaceutical Biologyen_US
dc.subjectTesting beyond ethnomedical claimsen_US
dc.subjectCytotoxic activityen_US
dc.subjectBrine shrimp lethalityen_US
dc.titleTesting beyond ethnomedical claims: brine shrimp lethality of some Tanzanian plantsen_US
dc.typeArticleen_US

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