Prevalence of metabolic syndrome and its risk factors in people living with aids using highly active antiretroviral therapy at care and treatment centres in ilala municipality 2009-2010
Loading...
Date
2012
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Hubert Kairuki Memorial University
Abstract
INTODUCTION: Metabolic syndrome refers to a clustering of cardiovascular risk
factors that include diabetes, obesity, aging, physical inactivity, dyslipidaemia,
hypertension and lipodystrophy. Lipodystrophy is more common in People Living with
AIDS using HAART, and there is little data on metabolic syndrome in people living with
AIDS using HAART in our environment.
OBJECTIVE: This study was carried out to determine the prevalence of metabolic
syndrome in PLWA using HAART in Ilala municipality between 2009/2010
METHODOLOGY: A total of 652 people aged above 18 years living with HIV/AIDS,
being tested for lipids profile and using HAART for not less than nine months were
recruited from five care and treatment centers out of 13 centers in Ilala district in Dar Es
Salaam. This study was done for one year from January, 2011 to December 2011.
RESULTS: Out of 652 people living with HIV/AIDS 332(50.9%) were females. About
60% of the participants were obese and about three quarters of obese participants were
aged 35-54 years, p= O.OOOl.Among 156 participants who had elevated BP only
37(23.7%) were using anti- hypertensive drugs, and two third of participants with
elevated BP, elevated serum Triglycerides, were aged 35-54 years., p = 0.0001.The
magnitude of metabolic syndrome in the PI based regimen was sigmficantly higher than
in NNRTIs based regimens, in those participants who had been using HAART for more
than 18 months withp value 0.0001.
CONCLUSION: My study observed that there was high prevalence of metabolic
syndrome in PLWA using HAART. with strong association of person age group,
dyslipidaemia, and duration in both NNRTIs and Pis based regimens.
Description
A dissertation submitted in partial fulfillment of the requirements for the MMed
internal medicine Programme of Hubert Kairuki Memorial University.
Keywords
Antiretroviral therapy, Ilala Municipality, HIV/AIDS
Citation
Riwa, D. N., 2012. Prevalence of metabolic syndrome and its risk factors in people living with aids using highly active antiretroviral therapy at care and treatment centres in ilala municipality 2009-2010. HKMU