Pattern and immediate outcome of neonates with congenital anomalies admitted at Kairuki, Temeke and Muhimbili Hospitals in 2018
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Date
2018
Authors
Journal Title
Journal ISSN
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Publisher
Hubert Kairuki Memorial University
Abstract
Burden of congenital anomalies on general health of children under five years has been shown to increase over the last decade. Globally back in 1990, under five deaths caused by congenital birth defects were5.88% while in 2016 the under five deaths were 8.31%. In Tanzania, 3.32% of under five years deaths were due to congenital birth defects in 1990 while in 2016 deaths were 3.2%. Monitoring trend of changes in the pattern of congenital anomalies and their associated factors over time is crucial for strengthening primary prevention to avert mortality and lifelong disability. This study aimed to identify the current pattern, risk factors associated wit hand immediate outcome of neonates with external congenital anomalies admitted within three urban hospitals in Dar es Salaam, Tanzania.
Methodology - this was a case control superconductivity October 2017 to June, 2018 whereby321neonates were enrolled. Mothers were interviewed using prepared questionnaires. Neonates were physically examined.Follow up for neonates with external congenital anomalies was done up until either discharge or death.Data was entered into computer using excel program and then analyzed using Epi Info Version 7.2.2.6 for windows. Results-Enrolled into study were107 cases and 214controls.Out of 107 cases, about 34 (31.8%)of neonates had Central nervous system anomalies followed by gastrointestinal tract system anomalies by26 (24.3%)and musculoskeletal system by25(23.4%). This study found a significant association between lack of maternal folic acid use and congenital anomalies (AOR = 27.17, 95% CI: 13.4, 53.5;P<0.01). Mortality from this study was in 17.8%. Conclusion-Central nervous system anomalies were the most common congenital anomalies observed in this study. Lack of maternal folic acid use was significantly associated with congenital anomalies.Mortality from this study was in 17.8%. Recommendation-Findings from this study calls for a multidisciplinary approach towards the prevention and management of congenital anomalies in Tanzania. It is recommended to increase sensitization of whole community on improving their folate status by promoting consumption of foods rich in natural folates and fortified foods.To create awareness amongst women on importance of folic acid supplementation and the need to follow up their pregnancies. To advocate for improved antenatal care services provision to healthcare workers with emphasis on basic prenatal screening for congenital anomalies.Government and policy makers to initiate national wide surveillance system for congenital anomalies by establishing birth defects registers in hospitals all over the country.
Description
A dissertation submitted in partial fulfillment of the requirement for the degree of Master of Medicine (Pediatrics and child health) of the Hubert Kairuki Memorial University
Keywords
Outcome of neonates, Congenital anomalies, Muhimbili Hospitals
Citation
Mrema, E.J. 2018. Pattern and immediate outcome of neonates with congenital anomalies admitted at Kairuki, Temeke and Muhimbili Hospitals in 2018.HKMU.