Handbook : quality practices in basic biomedical research / prepared for TDR by the scientific working group on quality practices in basic biomedical research
| dc.contributor.author | Moshi, Mainen J. | |
| dc.date.accessioned | 2023-08-23T05:53:16Z | |
| dc.date.available | 2023-08-23T05:53:16Z | |
| dc.date.issued | 2005 | |
| dc.description.abstract | The world’s population is facing serious health challenges in the form of newly emerging diseases or disease patterns e.g. avian influenza, severe acute respiratory syndrome (SARS), transmissible spongiform encephalopathies (bovine spongiform encephalopathy, Creutzfeldt-Jakob disease), human immunodeficiency virus (HIV), Ebola, and multidrug resistant diseases or organisms such as malaria. There are in- creasing difficulties in treating ‘old’ diseases such as trypanosomiasis, onchocerciasis, diabetes, hypertension and cancer. The problem is worsened by the changing age dis- tribution in populations, greater population movements that promote transmission of diseases, new practices in land use, agriculture and forestry, and changing world cli- mate, to name but a few. As a result, there is increased demand for new drugs and new principles for treatment, based on new knowledge about the causes and mechanisms of diseases, and for new methods of vector control. The search for these commodities and principles increases the need for scientific researchers and research programmes. With the continued restrictions in available funding, it is essential that basic scientific research as a whole, and especially in all fields connected with health issues, be con- ducted in a proper fashion using processes that minimize waste of resources and reduce the need for costly confirmation and repetition of work already performed. Today, research facilities in many universities, hospitals, government institutions and industries are used for basic scientific studies relevant to the discovery and develop- ment of new strategies for fighting disease including products with potential usefulness in health care. Data from these activities need to be reliable to ensure a solid basis for deciding whether to invest in further development of a strategy or product. Since the activities fall outside regulatory scope, i.e. they are not covered by, for example, the Organisation for Economic Co-operation and Development (OECD) Principles of Good Laboratory Practice (GLP), a need for guidance on quality practices in these areas has been recognized. This is why this handbook was commissioned. It should not be surprising, therefore, to find that some controversies in the scientific literature could probably have been resolved earlier, more easily and better if the prac- tical experimental conditions had been fully described, or if the supportive data had been properly collected. | en_US |
| dc.identifier.citation | UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases & Scientific Working Group on Quality Practices in Basic Biomedical Research. (2006). Handbook : quality practices in basic biomedical research / prepared for TDR by the Scientific Working Group on Quality Practices in Basic Biomedical Research. World Health Organization. | en_US |
| dc.identifier.uri | https://apps.who.int/iris/handle/10665/43512 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/1167 | |
| dc.language.iso | en | en_US |
| dc.subject | Biomedical | en_US |
| dc.subject | Research | en_US |
| dc.subject | Quality | en_US |
| dc.title | Handbook : quality practices in basic biomedical research / prepared for TDR by the scientific working group on quality practices in basic biomedical research | en_US |
| dc.type | Book chapter | en_US |