Effect of Zinc supplementation on duration of hospitalization in Tanzanian children presenting with acute pneumonia

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dc.contributor.authorFataki, Maulidi R.
dc.date.accessioned2020-02-28T05:07:19Z
dc.date.available2020-02-28T05:07:19Z
dc.date.issued2014
dc.description.abstractBackground: Zinc supplementation prevents incident pneumonia in children; however, the effect for pneumonia treatment remains unclear. Methods: A randomized, double-blind, placebo-controlled trial of zinc supplements (daily 25 mg) adjunct to antibiotic treatment of radiology-confirmed acute pneumonia was conducted among hospitalized children (6–36 months) in Dar es Salaam, Tanzania. Results: The trial was stopped early due to low enrollment, primarily owing to exclusion of children outside the age range and >3 days of prior illness. Among children enrolled (n = 94), zinc supplementation indicated no beneficial effect on the duration of hospitalization (IRR: 0.69; 95% CI 0.45–1.06; p = 0.09) or the proportion of children who were hospitalized for <3 days (RR: 0.85; 95% CI: 0.57–1.25; p = 0.40) or <5 days (RR: 1.01; 95% CI: 0.83–1.23; p = 0.92) (IRRs and RRs >1.0 favor zinc). Conclusions: Although underpowered, this randomized trial provided no evidence for a beneficial effect of zinc supplementation adjunct to antibiotics for hospitalized children.en_US
dc.identifier.citationFataki, M.R., Kisenge, R.R., Sudfeld, C.R., Aboud, S., Okuma, J., Mehta, S., Spiegelman, D. and Fawzi, W.W., 2014. Effect of zinc supplementation on duration of hospitalization in Tanzanian children presenting with acute pneumonia. Journal of tropical pediatrics, 60(2), pp.104-111.en_US
dc.identifier.other/doi.org/10.1093/tropej/fmt089
dc.identifier.urihttp://hdl.handle.net/123456789/282
dc.language.isoenen_US
dc.publisherJournal of tropical pediatricsen_US
dc.subjectzincen_US
dc.subjectPneumoniaen_US
dc.subjectMicronutrientsen_US
dc.titleEffect of Zinc supplementation on duration of hospitalization in Tanzanian children presenting with acute pneumoniaen_US
dc.typeArticleen_US

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