The pattern of respiratory manifestations in persons with HIV & AIDS in Dar Es Salaam, Tanzania twenty six years after the introduction of anti-retro viral drugs.
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Date
2023
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Hubert Kairuki Memorial University
Abstract
The pattern of respiratory manifestations in persons with HIV & AIDS in Dar
Es Salaam, Tanzania twenty six years after the introduction of anti-retro viral
drugs.
Magoma, Robert M.
ABSTRACT
Background: Human Immunodeficiency Virus
Objective: To assess respiratory manifestations among adults living with HIV/AIDS in
Dar es Salaam.
Methods: A cross-sectional hospital-based study was conducted at Dar es Salaam
public regional referral hospitals. Adults living with HIV/AIDS displaying respiratory
manifestations were the target population. A pre-designed questionnaire was the main
tool used for data collection. Univariate statistics was done and summarized using
median and corresponding inter-quartile range. Multivariable logistic regression was the
main method of data analysis.Alpha level of 5% was used as a limit of type I error in
findings.
Results: We successfully recruited and analysed 302 adult participants. Male: Female
=1.6:1. Median age of participant was 47
Conclusion: About one-fifth of all study participants had reported respiratory
manifestations. Tuberculosis was the most prevalent respiratory diagnosis. Actual age,
HIV stage, estimated time on ARVs, CD4+ counts as well as viral load were factors
associated with respiratory manifestations in this study population.
Recommendations: Modern and standard diagnostics need to be invested in order to
be able to improve diagnostic utilities of different respiratory pathologies associated
with HIV/AIDS in Tanzania. There are potential possibilities for pulmonary-based
diagnostic calculators for clinical predictive analyses as well as prognostication
purposes.
Description
A Dissertation Submitted in (partial) fulfilment of the Requirements for the Degree of Masters of Medicine (Internal Medicine) of the Hubert Kairuki Memorial University.
Keywords
Anti-retro viral, HIV & AIDS, Dar es salaam,Tanzania
Citation
Magoma,Robert M.,2023.The pattern of respiratory manifestations in persons with HIV & AIDS in Dar Es Salaam, Tanzania twenty six years after the introduction of anti-retro viral drugs.HKMU